Nodular Pulmonary Amyloidosis: A Complex Disease With Malignancy Association

Key Information
Source
BMJ Case Reports
Year
2017
summary/abstract

Pulmonary amyloidosis is a rare disease that incorporates deposition of amyloid microfibril material in the lung parenchyma. The condition generally presents as an indolent subacute-to-chronic pulmonary disease and requires tissue biopsy to establish the diagnosis.

Nodular pulmonary amyloidosis, a subtype of pulmonary amyloidosis, is characterised by special radiographic and pathological features. While the disease can be associated with inflammatory conditions; its association with mucosal-associated lymphoid tissue (MALT lymphoma) is unusual and carries management challenges. Herein, we illustrate a case study of nodular pulmonary amyloidosis associated with underlying MALT lymphoma in a patient with known systemic lupus erythematosus.

The aim of this article is to share the management experience of this complex condition with the medical community and to conduct an up-to-date literature review on nodular pulmonary amyloidosis.

Abstract Source
https://www.ncbi.nlm.nih.gov/pubmed/29038189
DOI
10.1136/bcr-2017-220428
Authors
Core JM, Alsaad AA, Jiang L, Patel NM
Organisation
Mayo Clinic Hospital Jacksonville, USA; Mayo Clinic Florida, USA