transthyretin
Oct 24, 2023
What is this summary about?This is a plain language summary of an article originally published in European Journal of Human Genetics. Transthyretin amyloidosis (…
Aug 27, 2023
The 30-month results of the phase 3 ATTRibute-CM trial provide the latest insight into the effects of acoramidis in people with transthyretin amyloid cardiomyopathy…
Jun 25, 2021
Background:
Transthyretin amyloidosis, also called ATTR amyloidosis, is a life-threatening disease characterized by progressive accumulation of misfolded…
Sep 22, 2020
Background:
Transthyretin amyloidosis (also known as ATTR amyloidosis) is a systemic, life-threatening disease characterized by transthyretin (TTR) fibril…
Jul 06, 2020
Importance: Many patients with systemic amyloidosis are underdiagnosed. Overall, 25% of patients with immunoglobulin light chain (AL) amyloidosis die within 6…
Mar 14, 2019
Background:
Transthyretin (TTR) amyloidosis is an underdiagnosed disease caused by destabilization of TTR due to pathogenic mutations or aging. Both pathogenic and…
Mar 21, 2017
The role of older generations in families with hereditary diseases has been recognised and associated to their function as guardians of the family's medical history…
Sep 19, 2016
Background:
The prognosis of amyloidosis is known to depend heavily on cardiac function and may be improved by identifying patients at highest risk for adverse…
Sep 13, 2016
Orthotopic liver transplantation (LT) was implemented as the inaugural disease-modifying therapy for hereditary transthyretin (ATTR) amyloidosis, a systemic…
May 16, 2016
Transthyretin-related cardiac amyloidosis is a progressive infiltrative cardiomyopathy that mimics hypertensive and hypertrophic heart disease and often goes…