Scientific Articles
Jul 04, 2018
Background:
Hereditary transthyretin amyloidosis is caused by pathogenic single-nucleotide variants in the gene encoding transthyretin ( TTR) that induce…
Jul 04, 2018
Background:
Patisiran, an investigational RNA interference therapeutic agent, specifically inhibits hepatic synthesis of transthyretin.
Methods:
In this phase 3…
Jul 01, 2018
Apolipoprotein A-I amyloidosis is a rare, autosomal dominant disorder of APOA-1 gene characterized by the deposition of apolipoprotein A-I in various organs and can…
Jun 25, 2018
Cerebral amyloidomas are rare cerebral mass lesions often associated with significant morbidity. Cerebral amyloid accumulation can be the result of a number of…
Jun 24, 2018
Background:
Fat embolism syndrome is a well-known complication in orthopedic and trauma surgery, caused by a massive release of fat into the circulation that can…
Jun 24, 2018
Primary localized cutaneous amyloidosis (PLCA) is characterized by deposition of keratinocyte-derived amyloid within the papillary dermis. PLCA often presents with…
Jun 18, 2018
Aims:
Wild-type transthyretin (ATTRwt) cardiac amyloidosis has emerged as an important cause of heart failure in the elderly. Atrial fibrillation (AF) commonly…
Jun 18, 2018
Aims:
Wild-type transthyretin (ATTRwt) cardiac amyloidosis has emerged as an important cause of heart failure in the elderly. Atrial fibrillation (AF) commonly…
Jun 18, 2018
Aims:
Wild-type transthyretin (ATTRwt) cardiac amyloidosis has emerged as an important cause of heart failure in the elderly. Atrial fibrillation (AF) commonly…
Jun 17, 2018
Introduction:
Amyloidosis accompanied by Sjogren's syndrome (SS) has been reported to occur primarily in the skin, lungs, tongue, and mammary gland. However, SS in…