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Objective: Amyloidosis is a term used to describe a group of diseases in which there is an extracellular deposition of amorphous fibrillar proteins known as amyloid…

Systemic amyloidoses are rare, complex diseases caused by misfolding of autologous protein. The presence of heart involvement is the most important prognostic…

Immunoglobulin light chain (AL) amyloidosis, the most common of the systemic amyloidosis, is characterized by the deposition of amyloid fibrils that derive from the…

Immunoglobulin light chain amyloidosis is the most common type of systemic amyloidosis. Hematopoietic stem cell transplantation (HCT) is an effective treatment…

It is believed that exercise is beneficial for the general well-being of patients with amyloidosis. If there are amyloid deposits in the heart then exercise should…

Many patients with AL amyloidosis should limit their fluid intake. This advice is extremely important but is often overlooked. Fluid intake should be steady and…

Peripheral neuropathy: Medications that may help to alleviate neuropathic pain include gabapentin, pregabalin and duloxetine. Medical staff can give advice…

Patients should tell the medical staff about any diarrhea they experience. Medications such as opioids (codeine and loperamide) may help by reducing gut motility.…

Both AL amyloidosis itself and treatment side effects may cause weight loss. Sometimes patients find it hard to eat and drink enough because of feeling generally…

Patients with AL amyloidosis may experience extreme tiredness, either due to the amyloidosis itself or as a side effect of some chemotherapy drugs. Tiredness can be…