Apr 02, 2025
AbstractObjectives: Proteinuria, amyloidosis, and kidney failure are the main long-term renal complications of familial Mediterranean fever (FMF). This study…
Apr 02, 2025
AbstractEnzyme catalysis is essential for molecular transformations. Here, we make use of amyloid, a fibrillar aggregate formed by stacking peptides with β-sheet,…
Apr 02, 2025
AbstractBackgroundGrowth-associated protein 43 (GAP-43) is a key protein involved in neuronal growth and synaptic plasticity. Alterations in GAP-43 levels have been…
Apr 02, 2025
AbstractAmyloid light-chain (AL) amyloidosis is characterized by the deposition of amyloid fibrils in various organs, although gallbladder involvement is rare. We…
Apr 02, 2025
AbstractClinical ConditionCardiac Amyloidosis (CA).Key QuestionsWhen should infiltrative cardiomyopathy be suspected, and what is the differential diagnosis? What…
Apr 02, 2025
AbstractAmyloid light-chain (AL) amyloidosis is characterized by the deposition of amyloid fibrils in various organs, although gallbladder involvement is rare. We…
Apr 02, 2025
AbstractBackgroundLeft atrial appendage occlusion (LAAO) is a valuable alternative therapy to anticoagulants for stroke prevention, and a representative study has…
Apr 02, 2025
Loneliness is a neuropsychiatric symptom that has been associated with cognitive impairment and dementia. We aimed to investigate whether depressive symptomatology…
Apr 01, 2025
ObjectiveIdentification of clinically meaningful subphenotypes of disease progression can enhance the understanding of disease heterogeneity and underlying…
Apr 01, 2025
PurposeAccording to a WHO statement, it has been asserted that there is no safe level of alcohol consumption regarding human health. Nevertheless, the relationship…