Clinical Trials and Research

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Amyloid Pathology Transmission in Lab Mice and Historic Medical Treatments
A UCL-led study has confirmed that some vials of a hormone used in discontinued medical treatments contained seeds of a protein implicated in Alzheimer's disease,…
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Blink' and You Won't Miss Amyloids: Engineering Team Just Found New Way to See Proteins That Cause Alzheimer's, Other Diseases
Tiny protein structures called amyloids are key to understanding certain devastating age-related diseases. Aggregates, or sticky clumped-up amyloids, form plaques…
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Amyloid Assemblies Once Believed to be Toxic Found to Play Key Role in Muscle Generation
Toxic protein assemblies, or "amyloids," long considered being key drivers in many neuromuscular diseases, also playing a beneficial role in the development of…
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US FDA Accepts Regulatory Submissions for Review of Tafamidis to Treat Transthyretin Amyloid Cardiomyopathy
Pfizer Inc. announced today that the US Food and Drug Administration (FDA) accepted for filing the company's New Drug Applications (NDAs) for tafamidis for the…
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Eidos Therapeutics Initiates ATTRibute-CM, a Phase 3 Study of AG10 in ATTR-CM with Registrational 12-month Endpoint
Eidos Therapeutics, Inc., today announced the initiation and design of its pivotal global Phase 3 trial (ATTRibute-CM) of AG10 in patients with Transthyretin (TTR)…
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